Horizontal transfer of domains in <i>ssrA</i> gene among Enterobacteriaceae

The tmRNA (transfer messenger RNA), encoded by ssrA gene, is involved in rescuing of stalled ribosomes a process called trans-translation. Additionally, regions the gene (coding for tmRNA) were reported to serve as integration sites various bacteriophages. Though variations genes reported, their functional relevance less studied. In this study, we investigated horizontal transfer (HGT) among members Enterobacteriaceae. This was done predicting recombination signals (belonging Enterobacteriaceae) using RDP5 (Recombination Detection Program 5). Our results revealed 7 belonging different species. We further showed that more domains present 3? end than 5? tmRNA. Of note, mRNA region many signals. Further, genera Yersinia, Erwinia, Dickeya and Enterobacter highly represented Sequence analysis presence class bacteriophages gene. locations phage recognition are comparable with Taken together, our diverse nature HGT which possibly due transduction mediated phages.